… Hematopoietic stem cell transplantation complications

The HTC Project endowment fund 2018-09-10T10:14:09+00:00

The HTC Project endowment funds

Give bone marrow transplant patients
a real chance to make a fresh start

What is a bone marrow transplant? Under what conditions is it prescribed?

When no available drug can treat patients facing cancer and serious blood diseases, transplant physicians replace their deficient blood cell “factory” with that of a matching donor. A long and complex procedure that requires the prior destruction of the patient’s immune system…


What are bone marrow transplant complications?

For the transplant of a new immune system to “take”, we must begin by destroying the sick one of the patient, which imposes heavy treatments. It is still very difficult to understand and anticipate the complications that may arise just after the transplant or in the months or years that follow this operation. These complications can be related to the conditioning treatments that prepare for the transplant, the weakness of the immune system of the patient which makes it, for a time, more susceptible to infections or very often to the attack of the patient’s tissues by the donor cells ( so-called Graft-versus-Host Disease or GvHD) reaction that can affect the skin, the liver … This disease affects more than half of the transplant patients and there is no efficient therapeutic resources at the moment. By joining our strengths in the frame of HTC Project, we intend to maximize the benefits of bone marrow transplantation to give patients a real chance « to make a frech start»

Pr. Jean-Hugues DALLE, Transplant Physician Département d’Hématologie de l’Hôpital Universitaire Robert DEBRÉ


About us

HTC Project empowers researchers and physicians to change the fate of patients facing the complications of bone marrow transplantation, the ultimate resort for patients suffering blood cancer or severe immunodeficiency, for whom no further therapeutic options are available.


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